Publications

Heterogeneity of the human immune response to malaria infection and vaccination driven by latent cytomegalovirus infection

Reena Mukhiya, Wim A Fleischmann, Jessica R. Loughland, Jo-Anne Chan, Fabian de Labastida Rivera, Dean Andrew, James G. Beeson, James S McCarthy, Bridget E Barber, J. Alejandro Lopez, Christian Engwerda,Richard Thomson-Luque, Michelle J Boyle

The impact of Plasmodium-driven immunoregulatory networks on immunity to malaria

Michelle J Boyle, Christian R Engwerda, Prasanna Jagannathan

Single cell transcriptomics shows that malaria promotes unique regulatory responses across multiple immune cell subsets

Nicholas L Dooley ^# 1 2, Tinashe G Chabikwa ^# 1, Zuleima Pava ¹, Jessica R Loughland ¹, Julianne Hamelink ^1 3, Kiana Berry ^1 4, Dean Andrew ¹, Megan S F Soon ¹, Arya SheelaNair ¹, Kim A Piera ⁵, Timothy William ^6 7, Bridget E Barber ^1 5 6, Matthew J Grigg ^5 6, Christian R Engwerda ¹, J Alejandro Lopez ^1 2, Nicholas M Anstey ^5 6, Michelle J Boyle ^{8 9 10 11 12}

Age-dependent changes in circulating Tfh cells influence development of functional malaria antibodies in children

Jo-Anne Chan ^1 2 3, Jessica R Loughland ^4 5, Lauren de la Parte ⁶, Satomi Okano ⁴, Isaac Ssewanyana ^7 8, Mayimuna Nalubega ^4 7 9, Felistas Nankya ⁷, Kenneth Musinguzi ⁷, John Rek ⁷, Emmanuel Arinaitwe ⁷, Peta Tipping ⁵, Peter Bourke ¹⁰, Dean Andrew ⁴, Nicholas Dooley ^4 11, Arya SheelaNair ⁴, Bruce D Wines ^1 2 12, P Mark Hogarth ^1 2 12, James G Beeson ^1 3 13, Bryan Greenhouse ¹⁴, Grant Dorsey ¹⁴, Moses Kamya ⁷, Gunter Hartel ⁴, Gabriela Minigo ^5 15, Margaret Feeney ¹⁴, Prasanna Jagannathan ⁶, Michelle J Boyle ^{16 17 18 19 20}

Adults with Plasmodium falciparum malaria have higher magnitude and quality of circulating T-follicular helper cells compared to children

Damian A Oyong ¹, Jessica R Loughland ², Megan S F Soon ³, Jo-Anne Chan ⁴, Dean Andrew ³, Bruce D Wines ⁵, P Mark Hogarth ⁵, Stuart D Olver ³, Alika D Collinge ³, Antiopi Varelias ⁶, James G Beeson ⁷, Enny Kenangalem ⁸, Ric N Price ⁹, Nicholas M Anstey ¹⁰, Gabriela Minigo ¹, Michelle J Boyle ¹¹

Th2-like T Follicular Helper Cells Promote Functional Antibody Production during Plasmodium falciparum Infection

Jo-Anne Chan ^1 2 3, Jessica R Loughland ⁴, Fabian de Labastida Rivera ⁴, Arya SheelaNair ⁴, Dean W Andrew ⁴, Nicholas L Dooley ⁴, Bruce D Wines ^1 2 5, Fiona H Amante ⁴, Lachlan Webb ⁴, P Mark Hogarth ^1 2 5, James S McCarthy ⁴, James G Beeson ^1 6 3, Christian R Engwerda ⁴, Michelle J Boyle ^1 4

IgM in human immunity to Plasmodium falciparum malaria

M J Boyle ^1 2 3, J A Chan ¹, I Handayuni ², L Reiling ¹, G Feng ^1 4, A Hilton ¹, L Kurtovic ^1 5, D Oyong ^2 6, K A Piera ², B E Barber ^2 3 7, T William ^7 8, D P Eisen ⁹, G Minigo ^2 6, C Langer ¹, D R Drew ¹, F de Labastida Rivera ³, F H Amante ³, T N Williams ^10 11, S Kinyanjui ^10 12, K Marsh ^10 12, D L Doolan ⁹, C Engwerda ³, F J I Fowkes ^1 13 14, M J Grigg ^2 7, I Mueller ^15 16 17, J S McCarthy ^3 18, N M Anstey ^2 6, J G Beeson ^1 4 19

Loss of complement regulatory proteins on red blood cells in mild malarial anaemia and in Plasmodium falciparum induced blood-stage infection

Damian A Oyong ^1 2, Jessica R Loughland ³, Arya SheelaNair ³, Dean Andrew ³, Fabian D L Rivera ³, Kim A Piera ¹, Timothy William ^4 5, Matthew J Grigg ^1 4, Bridget E Barber ^1 3 4, Ashraful Haque ³, Christian R Engwerda ³, James S McCarthy ^3 6, Nicholas M Anstey ¹, Michelle J Boyle ^7 8 9

Induction and Kinetics of Complement-Fixing Antibodies Against Plasmodium vivax Merozoite Surface Protein 3α and Relationship With Immunoglobulin G Subclasses and Immunoglobulin M

Damian A Oyong ^1 2, Danny W Wilson ^3 4, Bridget E Barber ^1 5 6, Timothy William ^5 7, Jianlin Jiang ⁸, Mary R Galinski ^8 9, Freya J I Fowkes ^{4 10 11 12 13}, Matthew J Grigg ^1 5, James G Beeson ^4 14 15, Nicholas M Anstey ^1 5, Michelle J Boyle ^1 4 6

Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia

Damian A Oyong ^1 2, Enny Kenangalem ^3 4, Jeanne R Poespoprodjo ^3 4 5, James G Beeson ^6 7 8, Nicholas M Anstey ¹, Ric N Price ^1 9, Michelle J Boyle ^1 6

Identification of Heparin Modifications and Polysaccharide Inhibitors of Plasmodium falciparum Merozoite Invasion That Have Potential for Novel Drug Development

Michelle J Boyle ^1 2, Mark Skidmore ^3 4, Benjamin Dickerman ⁵, Lynsay Cooper ³, Anthony Devlin ³, Edwin Yates ^3 4, Paul Horrocks ³, Craig Freeman ⁶, Wengang Chai ⁷, James G Beeson ^1 8

The Development of Plasmodium falciparum-Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission

Michelle J Boyle ^1 2, Prasanna Jagannathan ^1 3, Katherine Bowen ¹, Tara I McIntyre ¹, Hilary M Vance ¹, Lila A Farrington ¹, Alanna Schwartz ¹, Felistas Nankya ⁴, Kate Naluwu ⁴, Samuel Wamala ⁴, Esther Sikyomu ⁴, John Rek ⁴, Bryan Greenhouse ¹, Emmanuel Arinaitwe ⁴, Grant Dorsey ¹, Moses R Kamya ⁵, Margaret E Feeney ^1 6

Effector Phenotype of Plasmodium falciparum–Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations

Michelle J Boyle ¹, Prasanna Jagannathan ², Katherine Bowen ², Tara I McIntyre ², Hilary M Vance ², Lila A Farrington ², Bryan Greenhouse ², Felistas Nankya ³, John Rek ³, Agaba Katureebe ³, Emmanuel Arinaitwe ³, Grant Dorsey ², Moses R Kamya ⁴, Margaret E Feeney ⁵

Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria

Michelle J Boyle ¹, Prasanna Jagannathan ², Lila A Farrington ², Ijeoma Eccles-James ², Samuel Wamala ³, Tara I McIntyre ², Hilary M Vance ², Katherine Bowen ², Felistas Nankya ³, Ann Auma ³, Mayimuna Nalubega ³, Esther Sikyomu ³, Kate Naluwu ³, John Rek ³, Agaba Katureebe ³, Victor Bigira ³, James Kapisi ³, Jordan Tappero ⁴, Mary K Muhindo ³, Bryan Greenhouse ², Emmanuel Arinaitwe ³, Grant Dorsey ², Moses R Kamya ⁵, Margaret E Feeney ⁶

Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria

Michelle J Boyle ¹, Linda Reiling ², Gaoqian Feng ², Christine Langer ², Faith H Osier ³, Harvey Aspeling-Jones ⁴, Yik Sheng Cheng ¹, Janine Stubbs ², Kevin K A Tetteh ⁴, David J Conway ⁴, James S McCarthy ⁵, Ivo Muller ⁶, Kevin Marsh ³, Robin F Anders ⁷, James G Beeson ⁸

Sequential processing of merozoite surface proteins during and after erythrocyte invasion by Plasmodium falciparum

Michelle J Boyle ¹, Christine Langer, Jo-Anne Chan, Anthony N Hodder, Ross L Coppel, Robin F Anders, James G Beeson

Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development

Michelle J Boyle ¹, Danny W Wilson, Jack S Richards, David T Riglar, Kevin K A Tetteh, David J Conway, Stuart A Ralph, Jake Baum, James G Beeson

Interactions with heparin-like molecules during erythrocyte invasion by Plasmodium falciparum merozoites

Michelle J Boyle ¹, Jack S Richards, Paul R Gilson, Wengang Chai, James G Beeson

T-follicular helper cells in malaria infection and roles in antibody induction

Megan S F Soon ¹, Mayimuna Nalubega ², Michelle J Boyle ¹

Challenges and strategies for developing efficacious and long-lasting malaria vaccines

James G Beeson ^1 2 3, Liriye Kurtovic ^4 2, Carlota Dobaño ⁵, D Herbert Opi ^4 2, Jo-Anne Chan ⁴, Gaoqian Feng ^4 3, Michael F Good ⁶, Linda Reiling ⁴, Michelle J Boyle ^1 7

Recent insights into humoral immunity targeting Plasmodium falciparum and Plasmodium vivax malaria

Michelle J Boyle ¹, Linda Reiling ², Faith H Osier ³, Freya J I Fowkes ⁴

New approaches to studying Plasmodium falciparum merozoite invasion and insights into invasion biology

Michelle J Boyle ¹, Danny W Wilson, James G Beeson

Livening up pertussis vaccine development

Michelle Boyle

Broadening vaccine strategies to induce HIV broadly neutralizing antibodies

Michelle Boyle

The right adjuvant gives T follicular helper cells a boost

Michelle Boyle

A vaccine to kiss EBV goodbye

Michelle Boyle

Evaluating Complement-mediated Humoral Immunity to P. falciparum Blood stages

Michelle Boyle, Linda Reiling, James Beeson

Isolation of viable P. falciparum merozoites by membrane filtration

Michelle Boyle, David Wilson, James Beeson

6^th edition, 2013, EVIMalaR Glasgow, UK, edited by Moll K, Kaneko A, Scherf A, Wahlgren M.

Erythrocyte invasion assays with isolated viable P. falciparum merozoites

Michelle Boyle, David Wilson, James Beeson

6^th edition, 2013, EVIMalaR Glasgow, UK, edited by Moll K, Kaneko A, Scherf A, Wahlgren M